Favorable Outcome of Juvenile Dermatomyositis Treated without Systemic Corticosteroids

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Juvenile dermatomyositis without skin lesions

Introduction An 8-year-old Iranian girl was referred because she had progressive muscle weakness predominantly in lower limbs since about 2 years ago. She was not able to stand from a sitting position without help and had difficulty climbing stairs. She walked slowly and could not run like before. She had no complaint of dysphagia or dysphonia. She was born through a normal vaginal delivery and...

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Treatment and clinical outcome of juvenile dermatomyositis.

Autoimmune diseases in pediatric patients are heterogeneous, including systemic lupus erythematosus, juvenile rheumatoid arthritis, and juvenile dermatomyositis (JDM). JDM is a rare autoimmune disease involving multiple body systems and accounts for 85% of idiopathic inflammatory myopathies in children. JDM may lead to death or long-term disability; therefore, investigations into the important ...

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Juvenile dermatomyositis.

Juvenile dermatomyositis (JDMS) is a chronic inflammatory condition characterized by muscle weakness and a distinctive rash caused by underlying vasculopathy. Long-term complications include subcutaneous and muscular calcification, contractures and in some cases the gradual development of a second connective tissue disease. Early aggressive treatment with systemic immunosuppressants and other a...

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Juvenile dermatomyositis.

The clinical profile of 7 children and their follow-up is described. There was female preponderance with mate to female ratio of 1:6. The median age of onset was 6 years. All the patients had skin rash, muscle weakness and abnormal enzyme profile. Muscle biopsy was performed in 6 and was abnormal in all of them. The electromyogram (EMG) was performed in 6 and was found abnormal in five. All the...

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ژورنال

عنوان ژورنال: The Journal of Pediatrics

سال: 2010

ISSN: 0022-3476

DOI: 10.1016/j.jpeds.2009.09.008